| M18 |
Mahjoubfar, А.
Artificial Intelligence in Label-free Microscopy [Електронний ресурс] : Biological Cell Classification by Time Stretch / А. Mahjoubfar, C. L. Chen, B. Jalali. – Electronic text data. – Cham : Springer, 2017.
This book introduces time-stretch quantitative phase imaging (TS-QPI), a high-throughput label-free imaging flow cytometer developed for big data acquisition and analysis in phenotypic screening. TS-QPI is able to capture quantitative optical phase and intensity images simultaneously, enabling high-content cell analysis, cancer diagnostics, personalized genomics, and drug development. The authors also demonstrate a complete machine learning pipeline that performs optical phase measurement, image processing, feature extraction, and classification, enabling high-throughput quantitative imaging that achieves record high accuracy in label -free cellular phenotypic screening and opens up a new path to data-driven diagnosis. |
